Aesthetic applications with polynucleotides | biostimulators

What are polynucleotides?

Polynucleotides, the building blocks of DNA and RNA, are long chains of nucleotides linked by phosphodiester bonds. Their role in regenerative medicine is increasing, as they can promote cell regeneration and improve the healing process. These molecules also store and transmit genetic information.

Polynucleotides are valuable in medicine because of their biocompatible and bioactive properties. Their antioxidant effect protects the skin from oxidative stress (e.g. UV rays, exhaust fumes, dust, etc.).

Where are polynucleotides used?

Skin rejuvenation / skin regeneration

Polynucleotides are often used in aesthetic medicine to improve skin health. They promote the production of collagen and elastin, resulting in firmer and more youthful skin. Injection treatments with polynucleotides can reduce wrinkles and increase skin elasticity.

Wound healing

Polynucleotides can accelerate wound healing. They support cell proliferation and the formation of new blood vessels, allowing chronic and acute wounds to heal more quickly. For this reason, they are also used to treat scars.

Which areas of the body are treated with polynucleotides?

Polynucleotides can basically be used anywhere. They are most frequently used in the following areas:

Face
Neck
Neckline
Hands
Scars

What is the mode of action of polynucleotides?

Polynucleotides unfold their therapeutic effect through various mechanisms:

Cell regeneration: Polynucleotides promote cell proliferation, especially of fibroblasts that produce collagen.
Angiogenesis: Promotes the formation of new blood vessels, which improves blood circulation and the transport of nutrients in the tissue.
Inflammation inhibition: Polynucleotides reduce swelling and pain.
Antioxidant effect:
They neutralise free radicals and protect the cells from oxidative stress.

What are the advantages of polynucleotides over hyaluronic fillers?

Polynucleotides offer the following advantages over hyaluronic fillers:

Good compatibilityNatural molecules that the body accepts well.
Fewer side effectsCompared to synthetic materials, there are fewer side effects.
Wide range of applicationsCan be used in aesthetic medicine and regenerative medicine.

They have been in use here for over 20 years in some cases:

Orthopaedics:
- Used for tendon and joint injuries.
- Stimulation of cell regeneration in cartilage tissue.
Wound healing:
- Promotes healing in chronic wounds.
- Improvement of scarring.
Transplantation medicine:
- Support the regeneration of transplanted tissue.
- Improvement of tissue integration.

How long do polynucleotides last?

The effect of the polynucleotide treatment lasts for 6 to 12 months, depending on individual factors such as lifestyle and skin condition. The treatment can be repeated to refresh the effect.

Is there a risk?

Polynucleotide treatments may involve risks such as redness, swelling or slight pain at the injection site. Rare side effects include allergic reactions or infections. A thorough consultation and medical history are important to clarify the appropriate treatment and possible risks and to consider alternative options.

Which is better: Sculptra or polynucleotides?

Both options have their own advantages, and the choice often depends on your specific needs and goals or desired outcome.

Sculptra is a biostimulatory filler made from poly-L-lactic acid. It stimulates collagen production and provides long-term volume enhancement. It is particularly suitable for deeper wrinkles and volume loss.

Polynucleotides, on the other hand, improve skin texture and quality by promoting cell regeneration and providing antioxidant properties. This treatment is ideal for superficial skin improvements and overall skin health.

Conclusion and summary

Polynucleotide treatments are a promising alternative or supplement to fillers for natural skin improvements. It must be individually assessed whether this treatment is suitable or whether other methods are better.

What should you look out for when choosing a doctor?

When choosing a specialist, make sure that you use the term Specialist in Plastic and Aesthetic Surgery. Other designations such as beauty doctor, cosmetic surgeon, etc. are unprotected and not a sign of qualification (more on "What should you consider when choosing a specialist?„.

Make sure that you receive a comprehensive preliminary examination and information about the course of treatment, possible risks and the healing process.

Why should you come to us?

Extensive experience, maximum hygiene and infection protection, continuous further training and the utmost care are the basis of our practice. This is also reflected in the large number of positive patient reviews and our seals & awards.

Take advantage of our almost 20 years of experience for your desired change. Dr Michaela Montanari has been a member of the board of the German Society for Aesthetic Plastic Surgery (DGÄPC) since 2021.

Do you have any questions?

We will be happy to answer all your questions about the procedure, options, risks and healing of your hyaluronic acid injection. Arrange your personal consultation. We will advise you individually about your options.