PROFHILO® -
the biocompatible
Anti-ageing
Hyaluron freshness kick
for the skin

Profhilo

As we age, our body breaks down not only collagen and elastin but also the body's own hyaluronic acid in the tissue. The result: fine lines and wrinkles appear and the tissue loses volume and elasticity overall. PROFHILO® is ideal for visibly reversing the signs of time and slowing down skin ageing thanks to its unique, patented formulation.

What is PROFHILO® and what does it do?

PROFHILO® is a biocompatible, highly pure hyaluronic acid in which high and low molecular weight hyaluronic acid combine under the influence of heat to form a hybrid molecule. This special combination with the help of heating makes it possible to dispense with additives during production, which ensures very good tolerability and minimises the risk of side effects. The ingredients in PROFHILO® Hyaluronic acid binds water in the skin and moisturises the tissue from the inside out. Elastin and collagen formation is also stimulated. The skin appears significantly rejuvenated, plumper and firmer and finer overall.  Due to the special manufacturing process, PROFHILO® In contrast to non-cross-linked hyaluronic acid, it remains in the tissue up to thirty times longer.

Brief overview:

Duration of treatment:
20 minutes

treatment cycle:
2 - 3 treatments (4 weeks between treatment 1 and 2/ 3rd treatment after three months)

Anaesthesia:
not required

Follow-up treatment:
Special skin care if necessary

Load restrictions:
none

PROFHILO® is suitable for:

  • Facial rejuvenation
  • Neck
  • Décolleté rejuvenation
  • Hand rejuvenation
  • Body rejuvenation (e.g. knees, stomach, upper arms)

What is being done?

Yes, depending on the desired body area (Faceneck, décolleté, hands or other parts of the body), the hyaluronic acid is injected into defined injection points with a very fine needle according to a specially developed treatment scheme. Due to its special composition and the specially developed BAP injection technique (Bio Aesthetic Points), PROFHILO® The product then penetrates the tissue by itself and moisturises it completely.

In which area can PROFHILO® have it treated?

PROFHILO® is suitable as a filler wherever wrinkles, including parchment skin, have formed as a result of the ageing process. In other words, in all areas where the skin is naturally very thin and is most likely to visibly lose elasticity and show signs of fatigue. These include: Face, neck, décolleté, hands, the area above the knees, the inside of the upper arms and the stomach.

PROFHILO®-Treatment at a glance

Target:

Skin rejuvenation through a moisturising boost and stimulation of the body's own collagen and elastin production.

Consistency:

Very fluid, spreads evenly under the skin.

Application:

Injection at defined points (e.g. BAP technique on the face or neck). Profhilo contains a particularly highly concentrated, non-cross-linked hyaluronic acid, which intensively moisturises the skin, stimulates collagen and elastin formation and tightens the skin structure. The result is a naturally fresh, firmer complexion without a "plumped-up" effect

Effect:

First effects after a few weeks, full effect after approx. 4 weeks, lasts approx. 6 months.

Suitable for:

People with dry, tired or sagging skin who want a natural, fresher or firmer complexion

Is the PROFHILO®-treatment painful?

You only feel the few small punctures. For patients who are sensitive to pain, an anaesthetic cream can be applied before the treatment, which lasts for around 40 minutes.

How long does the PROFHILO®-treatment?

Depending on the treatment area, the treatment takes a maximum of 20 minutes and is therefore also suitable for a lunch break, for example. If an anaesthetic cream is to be applied beforehand, the total time is extended to approx. one hour. Immediately after the treatment, you can go about your normal daily activities without any problems. Possible small haematomas or puncture marks that are still visible in the first few days can be covered with make-up.

Does the PROFHILO®-treatment be repeated?

The result of a PROFHILO®-treatment lasts up to two years. For optimum results, a treatment cycle comprises two injections four weeks apart and a further injection after three months. An additional touch-up treatment is possible after 6 months if the findings are very pronounced.

Can I use the PROFHILO®-treatment with other treatments?

PROFHILO®- can be combined with other methods to further optimise the treatment result. The methods used in PROFHILO®- The hyaluronic acid contained in the ultrasound treatment visibly moisturises the skin. For an even greater rejuvenating effect, combination treatments with the micro-focussed ultrasound of Ultherapy®, Botulinum toxin, other hylauronic acid fillers, Radiesse® and operational measures be carried out.

Would you like a PROFHILO treatment or more information about your anti-ageing hyaluronic acid freshness boost for the skin? We will be happy to advise you.

What requirements should you fulfil?

  • As with any planned treatment, you should be in generally good health to aid healing after treatment.
  • There should be no acute skin diseases or inflammation in the treatment area.
  • The skin should not have any open wounds or infections.
  • You should not have a known allergy to hyaluronic acid or the other ingredients of Profhilo.
  • The treatment goal should be realistically assessed, e.g. improvement of skin structure and elasticity, not the treatment of deep wrinkles.
  • There should be a willingness to comply with aftercare recommendations and regular check-ups.
  • You must be of legal age.

What are the risks with Profhilo?

  • Redness or swelling may occur in the treated area.
  • Sometimes small bruises occur, but these usually disappear quickly.
  • In rare cases, slight pressure pain or a feeling of tension may occur.
  • Allergic reactions are possible but very rare.
  • Infections can be favoured by improper use or non-compliance with aftercare measures.

When should treatment not be carried out?

  • In case of known hypersensitivity or allergy to hyaluronic acid or one of the ingredients of Profhilo.
  • During an acute infection or inflammation in the skin area to be treated, e.g. herpes or bacterial infections.
  • For existing skin diseases or open wounds in the treatment area.
  • During pregnancy or breastfeeding, as no adequate safety studies are available to date.
  • In the case of autoimmune diseases or severe systemic diseases, the doctor treating the patient should be consulted before treatment.
  • If you are taking blood-thinning medication, there is an increased risk of bruising; individual medical clarification is advisable here.

What does science say about Profhilo?

Yes, Profhilo® has been tested in several clinical studies and in international Safety analyses examined. Both the skin effect and the tolerability of the treatment were assessed.

To the investigation

Studies show that Profhilo® improves Skin moisture, Elasticity and Skin structure can improve. It does not act like a classic filler, but supports the skin in the so-called Bio-remodelling, The natural renewal of skin components such as collagen and elastin.

[To the investigation],

[Info on Springer.com]

In clinical studies Improvement of fine lines, skin smoothness and skin texture observed. A large placebo-controlled study showed visible improvements, but individual measurements were not significantly stronger in all points than with placebo treatment. The effects are therefore considered Moderate and individually different. [link.springer.com], [springermedizin.de]

The safety of Profhilo® is well documented. In a worldwide evaluation of Over 40,000 treatments were No serious side effects were observed. The most common reactions were slight, temporary swelling, redness or minor bruising at the injection sites. [onlinelibr....wiley.com]

No. Studies show that Profhilo® Not a classic volume filler is. It is particularly suitable for Improvement in skin quality, not for targeted volume building or contouring.

[link.springer.com]

Profhilo® is mainly used for

  • decreasing skin elasticity
  • fine lines
  • dry or tired-looking skin

used when a Natural skin improvement without volume effect is desired. Whether the treatment makes sense in individual cases should be clarified by a doctor. [onlinelibr....wiley.com]

Yes. Further clinical studies are currently underway, including special applications for Tissue slackening and fat loss (e.g. Profhilo® Structura). Final results are not yet available in some cases.

[ichgcp.net], [clinicaltrials.gov]

Further scientific information

  • Overview of clinical studies (manufacturer's website):
    https://profhilo.com.hk/clinical-researches/
  • Safety analysis (peer review):
    https://onlinelibrary.wiley.com/doi/10.1155/2020/8159047
  • Placebo-controlled study (2026):
    https://link.springer.com/article/10.1007/s00266-026-05634-4

 

What should you look out for when choosing a doctor?

When choosing a specialist, make sure that you use the term Specialist in Plastic and Aesthetic Surgery. Other designations such as beauty doctor, cosmetic surgeon, etc. are unprotected and not a sign of qualification (more on "What should you consider when choosing a specialist?„.

Make sure that you receive a comprehensive preliminary examination and information about the course of treatment, possible risks and the healing process.

Why should you come to us?

Extensive experience, maximum hygiene and infection protection, continuous further training and the utmost care are the basis of our practice. This is also reflected in the large number of positive patient reviews and our seals & awards.

Take advantage of our almost 20 years of experience for your desired change. Dr Michaela Montanari has been a member of the board of the German Society for Aesthetic Plastic Surgery (DGÄPC) since 2021. 

What do patients say about us?

View all reviews

The reviews shown here come directly from our Google, Jameda and Trustindex profile. This is monitored and checked by the respective provider themselves. This means you can see real testimonials from our patients - transparent, up-to-date and reliable.

Do you have any questions?

We will be happy to answer all your questions about the procedure, possibilities, risks and healing of a treatment. Arrange your personal consultation. We will advise you individually about your options.

Our specialists for plastic and aesthetic surgery

Dr Michaela Montanari
Dr Michaela Montanari
Specialist in plastic and aesthetic surgery
Specialist for surgery
Chairperson of the
German Society for Aesthetic Plastic Surgery
dr-anna-maria-bugariu
Dr Anna Maria Bugariu
Specialist for
Plastic and aesthetic surgery
Inna Roeschies
Inna Roeschies
Specialist for
Plastic and aesthetic surgery